A “superstar” ingredient, according to Jeunesse Global “resveratrol” is an antioxidant that has, apparently, “been scientifically shown to extend lifespan by activating a dormant gene in DNA”.
A main component of its “extraordinary” RESERVE “nutritional gel that absorbs quickly to turbocharge your health”, resveratrol was reported by The Guardian to be so misunderstood that some scientists believe it is behind the “French paradox” which means to explain why French people have a low incidence of heart disease despite eating comparatively rich diets. The idea is that resveratrol occurs naturally in berries, grapes, and, therefore wine, which the French enjoy at larger volumes relative to Americans.
Working alongside RESERVE’s “supporting cast of other powerful antioxidants like açai, pomegranate, blueberry, dark sweet cherry, aloe vera, grapeseed, and green tea”, to “infuse your body with youthful vitality” resveratrol is quoted as helping Jeunesse Global to “target and engage” that “dormant gene in DNA”.
So not only can Jeunesse Global “delay aging at the cellular level” and “restore youthful vitality”, they now tell us that they can also make their customers live longer with a “naturally sweet supplement bursting with exotic fruit juices”. Is the “elixir of life” this easy to obtain? Can Jeunesse Global RESERVE’s “excellent defence against free radical damage” enable their customer’s cells to “stay healthier and live longer”? It’s hard not to get excited about those claims, especially when that means you can easily “enjoy the enduring effects of youth” thanks to Jeunesse Global.
The Jeunesse Global website states that the timeframe for seeing the results of their product’s “restorative powers” is “14-21 days to begin the anti-aging benefits and 5-7 days for an increased feeling of overall wellness and vitality”. I think I’d have better luck aging gracefully as a Tolkien elf from Lord of the Rings, or, better yet, as a vampire.
Seemingly the science behind Jeunesse Global’s latest prodigy of the product world is as simple as it containing “a host of powerful ingredients that repair free radical damage and protect cells against future harm. Your cells stay healthier, live longer, and leave you looking and feeling great”. It’s interesting that they pay lip service to the “free-radical theory of aging” here. This theory was conceived by Denham Harman in the 1950s and updated as the “mitochondrial theory” in 1972. It proposes that reacting with oxygen can cause damage to certain macromolecules including proteins and mitochondrial DNA.
On its website Jeunesse Global helpfully discusses “the problem with free radicals” describing how “molecules in nature (and in your body) typically have two electrons. Because of environmental harm, however, some molecules only have one electron—it’s “free” of its balancing partner and is unstable (or “radical”) as a result”. They go on, “when these unstable molecules encounter other healthy molecules, the free radical electron tries to pull another electron away to stabilize itself. That sets off a chain reaction as more molecules become imbalanced. This damaging process is known as oxidated stress”.
That’s actually an interesting block of information. That’s also where the interesting truth abruptly ends. The solution to “counteract oxidated stress” offered by Jeunesse Global is to consume “powerful antioxidants” that are “thought” to “slow the aging process related to free radical damage”. That sounds like more of a shot in the dark than a tried and tested formula that achieves results.
Antioxidants are helpful in reducing and preventing damage from free radical reactions, specifically because they “donate” electrons that neutralize the radical without forming another. But the hypothesis that large amounts of antioxidants will drastically reduce the radical damage that is associated with aging is ambitious to say the least.
While consuming a large amount of antioxidants is in no way harmful, after all this is why we’re encouraged to eat our five a day, repairing free radical damage isn’t as straightforward a process as Jeunesse Global would have us believe: antioxidants have limited benefits.
The RESERVE fact-sheet states that it is “the result of innovative science and ground-breaking research on behalf of medical professionals throughout the world”. It also references, “a substantial body of medical research and clinical trials”. They go on to say that studies show that the “antioxidant-yielding compound” resveratrol “can provide a wide range of benefits” and “may be one of the most effective anti-aging tools available”.
Unfortunately, “can” and “may” doesn’t exactly instill confidence and Jeunesse Global hasn’t said enough to convince me that they are in fact “redefining youth”, as they like to trumpet.
Citing their own research from 2010, the only independent study that’s referenced in the footnotes is that of Baur et al., (2006) which found that “resveratrol increases health and survival of mice on a high calorie diet”. Let’s look at that again, “…mice on a high calorie diet.”
This study found that resveratrol shifts the physiology of middle-aged mice on a high-calorie diet towards that of mice on a standard diet and significantly increases their survival. It was observed that resveratrol produced changes associated with longer lifespan, including increased insulin sensitivity and improved motor function, although nothing specific was mentioned regarding the appearance of anti-aging.
Nowhere does Jeunesse Global refer to the diet of its customers in relation to the effects RESERVE claims to have when consumed with the advised dosage of “daily consumption”. It would certainly increase credibility if Jeunesse Global qualified their product claims by characteristically saying that results “may” only be achieved if supplements are used as part of a high calorie diet, but they don’t.
The overall result of the data collected in the cited study shows that improving general health in mammals using small molecules is in fact an attainable goal. This points to new approaches for treating “diseases of ageing”. It’s interesting then that Jeunesse Global is still relying on marketing this research published about 9 years ago to support their claims. I suppose that means that in the decade that followed, no further evidence has been found to suggest that products containing resveratrol bear any relevance to DNA Repair or “anti-aging benefits”. Nice try, Jeunesse Global.